BESTMEDGRAPE: creating business opportunities from grape pomaces

Posted on August 7, 2020

We foresee the creation of at least one startup in each involved country to commercialize these products”

The BESTMEDGRAPE project was launched in September 2019 in 5 countries (Italy, France, Lebanon, Tunisia, Jordan), aiming at creating new business opportunities by transferring to potential entrepreneurs the scientific know-how on the sustainable use of grape pomace to manufacture cosmeceutical and nutraceutical products.

How will this project achieve its goal? How will new business opportunities be created from the residue of the grape? 

In a series of articles, we will walk you through the BESTMEDGRAPE project, from science to innovation, ecology, business, and more. In this article, we will shed light on the scientific process.

From pomace to cosmeceutical and nutraceutical products

The BESTMEDGRAPE project transfers to potential entrepreneurs the green and scalable methodologies and nanotechnologies to be used to transform the extracts obtained from grape byproducts into cosmeceutical and nutraceutical products. It will exploit the pomaces produced during winemaking, which are rich in bioactive compounds, to manufacture new products for food, cosmetic and pharmaceutical industries.

How? Maria Manconi, Research Fellow in Pharmaceutical Technology, University of Cagliari, explains that green, easy and scalable methodologies are applied to recover the active components from the grape pomaces. The phytocomplexes are extracted by maceration in ethanol and water, dried, loaded in nanocarriers and used to formulate cosmeceutical and nutraceutical products.

“Nanotechnology is the combination of science and technology involving systems in the nanoscale range, with size up to around 2-300 nanometers. It permits the creation of different materials and devices with a vast range of applications, such as nanomedicine, nanoelectronics and energy. In this project, we use phospholipid nanovesicles to load the grape phytocomplexes and deliver them to the human body”, she added.

Final result

Four varieties of grapes from each of the 5 countries have been selected and characterized along with the extracts obtained from these grapes. The content of the different extracts has been compared and the richer in bioactive compounds have been loaded in nanocarriers and used to formulate final products. 

The final products resulted from this process will be face mask, lotion, cream and other cosmeceutical products – which we will talk about it more in the upcoming articles, as well as pills, tablets, and other health-promoting products identified as food supplements and not drugs.

Business opportunities

This “easy” technology, as described by Manconi, will be transferred to potential entrepreneurs to manufacture these products at a pre-competitive level, therefore “we foresee the creation of at least one startup in each involved country to commercialize these products”, the scientist added.

Eco-friendly project

This process has a positive effect on the ecosystem, and this is also a goal for the BESTMEDGRAPE project. Maria Manconi explains that in many countries the grape pomaces are incorrectly disposed of in open fields without prior treatments, creating environmental problems and contaminations. In addition, the utilization of industrial by-products to manufacture cosmeceutical and nutraceutical products avoids the extensive cultivation of other plants to obtain the same active components, thus reducing water and energy consumption. 


Berytech has issued a call for applications to select 30 candidates for admission to the Technological Transfer Process, Mentorship and Guidance for Business Creation Program under the BESTMEDGRAPE project. Learn more here.